A practical and highly sensitive C3N4-TYR fluorescent probe for convenient detection of dopamine

文献情報

出版日 2015-06-15

DOI 10.1039/C5NR03316K

インパクトファクター 7.79

著者

Hao Li, Manman Yang, Juan Liu, Yalin Zhang, Yanmei Yang, Hui Huang, Yang Liu, Zhenhui Kang

原文を見る

要旨

The C3N4-tyrosinase (TYR) hybrid is a highly accurate, sensitive and simple fluorescent probe for the detection of dopamine (DOPA). Under optimized conditions, the relative fluorescence intensity of C3N4-TYR is proportional to the DOPA concentration in the range from 1 × 10−3 to 3 × 10−8 mol L−1 with a correlation coefficient of 0.995. In the present system, the detection limit achieved is as low as 3 × 10−8 mol L−1. Notably, these quantitative detection results for clinical samples are comparable to those of high performance liquid chromatography. Moreover, the enzyme-encapsulated C3N4 sensing arrays on both glass slide and test paper were evaluated, which revealed sensitive detection and excellent stability. The results reported here provide a new approach for the design of a multifunctional nanosensor for the detection of bio-molecules.

掲載誌

Nanoscale

CiteScore: 12.1

自己引用率: 5.2%

年間論文数: 1681

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