Silver nanostructures in laser desorption/ionization mass spectrometry and mass spectrometry imaging

文献情報

出版日 2015-07-27

DOI 10.1039/C5AN00943J

インパクトファクター 4.616

著者

Justyna Sekuła, Joanna Nizioł, Wojciech Rode, Tomasz Ruman

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要旨

Silver nanoparticles have been successfully applied as a matrix replacement for the laser desorption/ionization time-of-flight mass spectrometry (LDI-ToF-MS). Nanoparticles, producing spectra with highly reduced chemical background in the low m/z region, are perfectly suited for low-molecular weight compound analysis and imaging. Silver nanoparticles (AgNPs) can efficiently absorb ultraviolet laser radiation, transfer energy to the analyte and promote analyte desorption, but also constitute a source of silver ions suitable for analyte cationisation. This review provides an overview of the literature on silver nanomaterials as non-conventional desorption and ionization promoters in LDI-MS and mass spectrometry imaging.

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Analyst

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Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

Silver nanostructures in laser desorption/ionization mass spectrometry and mass spectrometry imaging

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