Old is new again: a chemical probe for targeting mitochondria and monitoring mitochondrial membrane potential in cells

文献情報

出版日 2015-06-19

DOI 10.1039/C5AN00918A

インパクトファクター 4.616

著者

Lu Zhang, Wenwen Liu, Xianhong Huang, Guanxin Zhang, Xuefei Wang, Zhuo Wang, Deqing Zhang, Xingyu Jiang

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要旨

Here, we explore the new application of an old molecule. We find that the tetraphenylethene-indolium molecule (TPE-indo) can both image the mitochondria (in the aggregated state), and indicate mitochondrial activity by the fluorescence change of TPE-indo. TPE-indo shows good photostability, longer emission wavelength, targeting effect for mitochondria, and better response to the changes of the mitochondrial membrane potential (ΔΨm).

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Analyst

CiteScore: 7.8

自己引用率: 5.6%

年間論文数: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

Old is new again: a chemical probe for targeting mitochondria and monitoring mitochondrial membrane potential in cells

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