Temperature-sensitive nanogels: poly(N-vinylcaprolactam) versus poly(N-isopropylacrylamide)

文献情報

出版日 2011-12-16

DOI 10.1039/C2PY00485B

インパクトファクター 5.582

著者

Jose Ramos, Ainara Imaz, Jacqueline Forcada

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要旨

Poly(N-isopropylacrylamide) (PNIPAM) and poly(N-vinylcaprolactam) (PVCL) are temperature-responsive polymers which show a lower critical solution temperature (LCST) around 32 °C in aqueous solutions. Nanogels based on these temperature sensitive polymers swell at low temperatures and collapse at high ones, showing a volume phase transition temperature (VPTT) near physiological temperature. This unique behavior makes these nanogels attractive for biotechnological applications. PNIPAM is the building block of a huge amount of nanogels reported in the literature. However, PVCL is especially interesting due to the fact that it is very stable against hydrolysis and biocompatible. In this mini-review, various synthesis procedures together with the functionalization of different PNIPAM- and PVCL-based nanogels are revised and compared.

掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Temperature-sensitive nanogels: poly(N-vinylcaprolactam) versus poly(N-isopropylacrylamide)

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