Synthesis of a controlled three-faced PAMAM particle

文献情報

出版日 2011-07-14

DOI 10.1039/C1PY00146A

インパクトファクター 5.582

著者

Mathieu Arseneault, Philippe Dufour, Isabelle Levesque, Jean-François Morin

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要旨

We report the synthetic proof-of-concept for a three-faced particle based on a PAMAM dendrimer in which each face bears a different labile protecting group. This new strategy yields a controlled, well-defined and monodisperse dendrimer. To achieve this, a tri-orthogonal strategy was employed through Sonogashira coupling and Cu(I)-catalyzed Huisgen [2 + 3] dipolar cycloaddition (“click” chemistry). The afforded dendrimer is well suited for further development in a variety of fields as each branch can be addressed individually for functionalization.

掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Synthesis of a controlled three-faced PAMAM particle

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Polymer Chemistry

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