Polymer micelles decorated by gadolinium complexes as MRI blood contrast agents: design, synthesis and properties

文献情報

出版日 2010-08-06

DOI 10.1039/C0PY00117A

インパクトファクター 5.582

著者

Mathurin Grogna, Rudi Cloots, André Luxen, Christine Jérôme, Catherine Passirani, Nolwenn Lautram, Jean-F. Desreux, Christophe Detrembleur

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要旨

New micellar macrocontrast agents with improved contrast at high frequencies were designed by grafting a gadolinium based contrast agent onto functional stealth micelles formed by poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO-b-PCL) in water. As evidenced by relaxometry measurements and the hemolytic CH50 test, the new contrast agents are of interest as MRI blood pool agents.

掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Polymer micelles decorated by gadolinium complexes as MRI blood contrast agents: design, synthesis and properties

文献情報

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