Electrochemical assay of superoxide based on biomimetic enzyme at highly conductive TiO2 nanoneedles: from principle to applications in living cells

文献情報

出版日 2009-04-07

DOI 10.1039/B902150G

インパクトファクター 6.222

著者

Yongping Luo, Yang Tian, Qi Rui

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要旨

A novel strategy for extremely durable, reliable, and selective in situ real-time determination of superoxide anion (O2˙−) based on direct electron transfer of a biomimeticsuperoxide dismutase (SOD), Mn3(PO4)2, at highly conductive TiO2 nanoneedles is reported for the first time, and is further exploited for the determination of O2˙− from living normal and cancer ovary cells directly adhered onto the modified surface, suggesting that O2˙− might be proposed as a biomarker of cancer.

掲載誌

Chemical Communications

CiteScore: 8.6

自己引用率: 4.7%

年間論文数: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

Electrochemical assay of superoxide based on biomimetic enzyme at highly conductive TiO2 nanoneedles: from principle to applications in living cells

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