Cell Chemical Biology

Cell Chemical Biology (originally Chemistry & Biology) is a Cell Press journal that aims to publish and promote the most important advances in chemical biology with integrity, responsiveness, fairness, and friendliness. Chemical biology is a unique discipline that harnesses the power of chemistry to deliver profound molecular insights into biological function and disease etiology and develop solutions for life sciences, biotechnology, and human health. Cell Chemical Biology encourages submission of basic, translational, and clinical research articles that provide significant conceptual advancements of broad general interest to researchers within the biological sciences, the biomedical sciences, and associated fields. Research areas that we consider within our scope include but are not limited to cancer biology, immunology, cell biology, microbiology, virology, RNA biology, synthetic biology, protein engineering, genome editing, drug discovery, metabolism, and physiology. We are interested in papers that report molecular mechanisms underlying cellular processes or disease biology; those that report new therapeutics derived from utilizing chemical biology tools; and those that report technologies that perturb, visualize, or measure biological processes. Examples of chemical or molecular tools include but are not confined to nucleic acids and/or their modifications, small molecules, antibodies, biologics, probes, engineered proteins, metabolites, lipids, sugars, and post-translational modifications. We also welcome submissions reporting significant technical advancements in molecular probes, sensors, tools, and technologies, including a proof-of-principle demonstration that the new methodology/tool will help address important questions in biomedical research that are of interest to our broad readership (from basic scientists to clinicians).