Inhibition of lysozyme's polymerization activity using a polymer structural mimic

文献情報

出版日 2018-05-29

DOI 10.1039/C8PY00545A

インパクトファクター 5.582

著者

D. L. Morris, T. C. Leeper, C. J. Ziegler

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要旨

Hen egg white lysozyme (HEWL) is a green catalyst capable of polymerizing 2-ethynylpyridine. 1,3-di(2-pyridyl)propane (DPP) is a mimic of the polymer repeating unit, and its interaction with HEWL reveals structural insight into the mechanism of polymerization. These interactions were probed using NMR methods, including diffusion-ordered spectroscopy (DOSY) and saturation transfer difference (STD) measurements, and the structure of HEWL with DPP in the active site was elucidated by X-ray methods.

掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

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Inhibition of lysozyme's polymerization activity using a polymer structural mimic

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