A practical approach for the synthesis of oxindole and isatin derivatives by Pd-catalyzed intramolecular amination

文献情報

出版日 2017-09-05

DOI 10.1039/C7QO00710H

インパクトファクター 5.281

著者

Yubo Pang, Mingyu Guan, Runsheng Zeng, Yingsheng Zhao

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要旨

Oxindole/isatin-N-acetamide derivatives are a class of important pharmacologically active compounds. Herein, we report a practical protocol for the synthesis of such derivatives based on palladium-catalyzed intramolecular amination. Various functional groups are tolerated, and the corresponding products are obtained in moderate to good yields, highlighting the potential synthetic utility of this method.

掲載誌

Organic Chemistry Frontiers

CiteScore: 7.8

自己引用率: 8.7%

年間論文数: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

A practical approach for the synthesis of oxindole and isatin derivatives by Pd-catalyzed intramolecular amination

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