Enantio- and diastereoselective synthesis of tetrahydrofuro[2,3-b]furan-2(3H)-one derivatives and related oxygen heterocycles via an asymmetric organocatalytic cascade process

文献情報

出版日 2017-08-28

DOI 10.1039/C7QO00621G

インパクトファクター 5.281

著者

Wei-Wei Zhao

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要旨

Tetrahydrofuro[2,3-b]furan-2(3H)-one derivatives bearing four stereogenic centers were achieved via an asymmetric organocatalytic cascade process with excellent stereoselectivity in one single operation and H2O as the only side product. The α,β-unsaturated carboxylic acid plays two important roles in the cascade process: the Michael acceptor and acidic co-catalyst for enamine catalysis.

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Organic Chemistry Frontiers

CiteScore: 7.8

自己引用率: 8.7%

年間論文数: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

Enantio- and diastereoselective synthesis of tetrahydrofuro[2,3-b]furan-2(3H)-one derivatives and related oxygen heterocycles via an asymmetric organocatalytic cascade process

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