Synthetic strategies towards mycolactone A/B, an exotoxin secreted by Mycobacterium ulcerans

文献情報

出版日 2017-08-28

DOI 10.1039/C7QO00608J

インパクトファクター 5.281

著者

Sarah Saint-Auret, Hajer Abdelkafi, Didier Le Nouen, Philippe Bisseret, Nicolas Blanchard

原文を見る

要旨

Mycolactone A/B, a complex polyketidic macrolide secreted by Mycobacterium ulcerans, has been synthesized using catalytic and/or asymmetric reactions. Several palladium-catalyzed reactions were investigated for forging key σ-bonds as well as a particularly challenging hydroboration reaction of a functionalized and sterically demanding 1,1-disubstituted exo-alkene. The full account of these investigations is discussed.

掲載誌

Organic Chemistry Frontiers

CiteScore: 7.8

自己引用率: 8.7%

年間論文数: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

Synthetic strategies towards mycolactone A/B, an exotoxin secreted by Mycobacterium ulcerans

文献情報

おすすめジャーナル

関連文献

DNA strand scission induced by a non-thermal atmospheric pressure plasma jet

Role of excited-state hydrogen detachment and hydrogen-transfer processes for the excited-state deactivation of an aromatic dipeptide: N-acetyl tryptophan methyl amide

Raman spectroscopic studies of defect structures and phase transition in hyper-stoichiometric UO2+x

Collision-induced dissociation (CID) of guanine radical cation in the gas phase: an experimental and computational study

Triplet formation of 6-azauridine and singlet oxygensensitization with UV light irradiation

Formation of electro-conductive titanium oxide fine particles by pulsed UV laser irradiation

Molecular dynamics simulations of N,N,N,N-tetramethylammonium dicyanamide plastic crystal and liquid using a polarizable force field

Interrogating the ultrafast dynamics of an efficient dye for sunlight conversion

Relative stability of thiol and selenol based SAMs on Au(111) — exchange experiments

Stabilization of Au at edges of bimetallic PdAu nanocrystallites

こちらもおすすめ

4-アミノフェノール酸ナトリウム水和物とは何ですか？

Methyl 3-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-histidinateの代替品はありますか？

4-Boc-2-哌嗪甲酸の市場動向や研究トレンドはどうですか？

4,4'-二羟甲基联苯の物理化学的性質は何ですか？

5-甲硫基戊腈はどの業界で使用されていますか？

CAS番号1311961-50-8の化合物はどのように合成されますか？

6-ブロモベンジジミダゾール-2-カルビルデオキシドはどのように保存すればよいですか？

Boc-N-甲基氨甲环酸とは何ですか？

乙基三氟硼酸钾はどのように合成されますか？

2-フロウロ-5-クロロ-4-アミノフェノールはどのように保存すればよいですか？

掲載誌

Organic Chemistry Frontiers

おすすめ化合物

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-Diacetyloxy-15-[(2R,3S)-3-benzamido-3-phenyl-2-(2,2,2-trichloroethoxycarbonyloxy)propanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

N3-ethylpyridine-3,4-diamine

1-(4-Methyl-2-thienyl)methanamine

1-Chloro-2-(chlorophenylmethyl)benzene

Xylometazoline EP Impurity F

おすすめサプライヤー