Synthesis of substituted oxazoles via Pd-catalyzed tandem oxidative cyclization

文献情報

出版日 2017-09-04

DOI 10.1039/C7QO00517B

インパクトファクター 5.281

著者

Wei Zhang, Wenlong Yu, Qiangqiang Yan, Zhanxiang Liu

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要旨

A novel method for the synthesis of multisubstituted oxazoles by palladium-catalyzed oxidative cyclization of N-acyl enamides has been developed. The reaction employs readily available iodobenzenes and enamides as the starting materials under mild reaction conditions and provides a reliable way to achieve versatile substituted oxazole derivatives.

掲載誌

Organic Chemistry Frontiers

CiteScore: 7.8

自己引用率: 8.7%

年間論文数: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

Synthesis of substituted oxazoles via Pd-catalyzed tandem oxidative cyclization

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