Self-assembly of random co-polymers for selective binding and detection of peptides

文献情報

出版日 2017-12-19

DOI 10.1039/C7PY01947E

インパクトファクター 5.582

著者

Bo Zhao, Mahalia A. C. Serrano, Jingjing Gao, Jiaming Zhuang

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要旨

Amphiphilic random co-polymers, which form stable reverse micelle-type assemblies, have been designed and synthesized. We demonstrate that the reverse micelles, formed by these co-polymers are capable of selectively binding peptides through electrostatic interactions, indicating that these random polymers can self-organize into functionally selective materials. Moreover, these random co-polymers also enable the ordered co-crystallization of matrix and extract guest molecules, giving rise to substantial signal enhancements during MALDI-MS detection. Together, these observations represent an excellent example of how random polymers can self-assemble into ordered, functional materials.

掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

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Self-assembly of random co-polymers for selective binding and detection of peptides

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