Cationic polythiophenes as responsive DNA-binding polymers

文献情報

出版日 2013-09-23

DOI 10.1039/C3PY01069D

インパクトファクター 5.582

著者

Webster L. Santos, John B. Matson, Regina C. So

原文を見る

要旨

A new water soluble cationic polythiophene derivative, poly(N,N,N-trimethyl-3-(2-(thiophen-3-yl)acetamido)propan-1-aminium iodide), was synthesized via two consecutive post-polymerization functionalizations of poly(methyl 2-(thiophen-3-yl)acetate). This conjugated polymer binds DNA at N/P = 5 and forms polyplexes at N/P = 10. Its potential use as a theranostic gene delivery vehicle is investigated here.

掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Cationic polythiophenes as responsive DNA-binding polymers

文献情報

おすすめジャーナル

関連文献

Anomalous high photovoltages observed in shish kebab-like organic p–n junction nanostructures

Chalcone derivatives as highly versatile photoinitiators for radical, cationic, thiol–ene and IPN polymerization reactions upon exposure to visible light

A novel route for polymerisation of thiophene based conducting polymers using trace-free oxidants

Versatile injectable supramolecular hydrogels containing drug loaded micelles for delivery of various drugs

Synthesis of biomimetic co-polypeptides with tunable degrees of phosphorylation

Acetyl protected thiol methacrylic polymers as effective ligands to keep quantum dots in luminescent standby mode

Manganese(iii) acetylacetonate initiated RAFT polymerizations: an alternative and versatile RAFT initiator

Happy New Year from Polymer Chemistry

A biomimic pH-sensitive polymeric prodrug based on polycarbonate for intracellular drug delivery

Facile synthesis of chain end functionalized polyethylenes via epoxide ring-opening and thiol–ene addition click chemistry

こちらもおすすめ

除水剤ALT-201は安全ですか？

「邻羟基阿托伐他汀内酯标准品」に適用される法規ガイドelinesは何ですか？

メチル（3R）-3-アミノ-2,3-ジヒドロ-1-ベンゾファンラニン-5-カルボイル酸塩塩酸塩の主な用途は何ですか？

トランス-4-メチルピロリジン-3-オール塩酸塩はどのように合成されますか？

硫雜環丁烷-1,1-二氧化物は安全ですか？

ブラエリリンの主な用途は何ですか？

9-ヒドロキシエリプチシネ塩酸塩はどのように合成されますか？

5-塩素-2-(メチルアミノ)フェニル-(2-塩素フェニル)メタン酮の物理化学的性質は何ですか？

1-[2-(4-甲氧基-苯氧基)-乙基]-哌嗪はどのように保存すればよいですか？

2-[3-(4-甲氧基フェニル)プロピル]-4,4,5,5-四メチル-1,3,2-ドイボロロールアンの主な用途は何ですか？

掲載誌

Polymer Chemistry

おすすめ化合物

2-Sulfanyl-3-pentanone

Methyl 2-hydroxydodecanoate

(3R,5R)-1-[(Benzyloxy)carbonyl]-5-methyl-3-piperidinecarboxylic acid

2,2',3,3',4,5,5',6,6'-Nonabromobiphenyl

6-(2-Methylphenyl)-2-pyridinecarboxylic acid

おすすめサプライヤー